U.S. Frontiers of Engineering (USFOE) symposia bring together 100 outstanding engineers (ages 30 to 45) to exchange information about leading-edge technologies in a range of engineering fields. The 2007 symposium covered engineering trustworthy computer systems, control of protein conformations, biotechnology for fuels and chemicals, modulating and simulating human behavior, and safe water technologies. Papers in this volume describe leading-edge research on disparate tools in software security, decoding the “mechanome,” corn-based materials, modeling human cultural behavior, water treatment by UV irradiation, and many other topics. A speech by dinner speaker Dr. Henrique (Rico) Malvar, managing director of Microsoft Research, is also included. Appendixes provide information about contributors, the symposium program, summaries of break-out sessions, and a list of participants. This is the thirteenth volume in the USFOE series. Table of Contents Front Matter Engineering Trustworthy Computer Systems Introduction–Ana I. Antón and John Dunagan Privacy in a Networked World–Rebecca N. Wright Unifying Disparate Tools in Software Security–Greg Morrisett Usable Security: Oxymoron or Challenge?–Diana K. Smetters Control of Protein Conformations Introduction–Donald J. Leo The Evolutionary Design of Proteins–Rama Ranganathan Lighting Up the Mechanome–Matthew J. Lang Biotechnology for Fuels and Chemicals Introduction–Richard T. Elander and Vijay Singh Corn-Based Materials–Sanjay V. Malhotra, Vineet Kumar, Anthony East, and Michael Jaffe Process Review of Lignocellulose Biochemical Conversion to Fuel Ethanol–Bruce S. Dien Sustainable Biorefineries–Carina Maria Alles and Robin Jenkins Modeling and Simulating Human Behavior Introduction–Christian Lebiere and Robert Wray Computational Cognitive Neuroscience and Its Applications–Laurent Itti Barriers, Bridges, and Progress in Cognitive Modeling for Military Applications–Kevin A. Gluck Modeling of Culturally Affected Human Behavior–Michael van Lent, Mark Core, Steve Solomon, Milton Rosenberg, Ryan McAlinden, and Paul Carpenter Safe Water Technologies Introduction–Carol R. Rego and Paul K. Westerhoff Ultraviolet Irradiation: An Age-Old Emerging Technology for Water Treatment–Karl G. Linden Membrane Processes to Address the Global Challenge of Desalination–Amy E. Childress Biological Treatments of Drinking Water–Jess C. Brown Distribution Systems: The Next Frontier–Vanessa L. Speight Appendixes Breakout Sessions Contributors Program Participants